BDBM321133 (S)-methyl (8-((2-amino-2,4-dimethylpentyl)oxy)-6H-isochromeno[3,4-c]pyridin-4-yl)carbamate::US10174044, Example 64

SMILES COC(=O)Nc1nccc-2c1OCc1cc(OC[C@@](C)(N)CC(C)C)ccc-21

InChI Key InChIKey=WKVUIHAGESSZGM-NRFANRHFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321133   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM321133((S)-methyl (8-((2-amino-2,4-dimethylpentyl)oxy)-6H...)
Affinity DataIC50:  7.80nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent