BDBM328646 (S)-isobutyl (2-(acetamidomethyl)- 4-((4-fluorophenyl)sulfonyl)-3,4- dihydro-2H-benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 30F

SMILES CC(C)COC(=O)Nc1ccc2O[C@@H](CNC(C)=O)CN(c2c1)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=MRESDKWHEDCPFC-SFHVURJKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328646   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM328646((S)-isobutyl (2-(acetamidomethyl)- 4-((4-fluorophe...)
Affinity DataIC50:  54.3nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent