BDBM328836 (S)-tert-butyl (4-((4- fluorophenyl)sulfonyl)-2- (methylsulfonamidomethyl)-3,4- dihydro-2H-benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 37F

SMILES CC(C)(C)OC(=O)Nc1ccc2O[C@@H](CNS(C)(=O)=O)CN(c2c1)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=QIRHYRGXHNZRTH-INIZCTEOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328836   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM328836((S)-tert-butyl (4-((4- fluorophenyl)sulfonyl)-2- (...)
Affinity DataIC50:  11.1nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent