BDBM329649 US11001583, Compound 5::US9663515, Compound 5

SMILES CC[C@@H]1N(C[C@@H]2CC[C@@H](OC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](COC)c1ccc(cc1)S(=O)(=O)CC

InChI Key InChIKey=QUVQURVCUHKPKP-PAWHMVCQSA-N

Data  2 KI

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329649   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals, LLC

US Patent
LigandPNGBDBM329649(US11001583, Compound 5 | US9663515, Compound 5)
Show SMILES CC[C@@H]1N(C[C@@H]2CC[C@@H](OC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](COC)c1ccc(cc1)S(=O)(=O)CC
Show InChI InChI=1S/C28H36F3N3O5S/c1-4-24-26-21(15-34(24)14-18-6-11-25(39-16-18)28(29,30)31)12-20(13-32-26)27(35)33-23(17-38-3)19-7-9-22(10-8-19)40(36,37)5-2/h7-10,12-13,18,23-25H,4-6,11,14-17H2,1-3H3,(H,33,35)/t18-,23-,24-,25+/m0/s1
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals, LLC

US Patent
LigandPNGBDBM329649(US11001583, Compound 5 | US9663515, Compound 5)
Show SMILES CC[C@@H]1N(C[C@@H]2CC[C@@H](OC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](COC)c1ccc(cc1)S(=O)(=O)CC
Show InChI InChI=1S/C28H36F3N3O5S/c1-4-24-26-21(15-34(24)14-18-6-11-25(39-16-18)28(29,30)31)12-20(13-32-26)27(35)33-23(17-38-3)19-7-9-22(10-8-19)40(36,37)5-2/h7-10,12-13,18,23-25H,4-6,11,14-17H2,1-3H3,(H,33,35)/t18-,23-,24-,25+/m0/s1
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid