BDBM33254 phthalazine-based compound, 5

SMILES NCc1ccc(Nc2nnc(Nc3ccc(cc3)C3=NCCN3)c3ccccc23)cc1

InChI Key InChIKey=DQOOPKPLAFDHEQ-UHFFFAOYSA-N

Data  5 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 33254   

TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
Novartis Institute For Tropical Diseases

LigandChemical structure of BindingDB Monomer ID 33254BDBM33254(phthalazine-based compound, 5)
Affinity DataIC50: 1.06E+4nM Kd:  1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details Article
PubMed