BDBM34152 CHEMBL362628::E-6801
SMILES CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc12
InChI Key InChIKey=RZAXUKVIIWUIOM-UHFFFAOYSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 34152
Affinity DataKi: 0.580nMAssay Description:Binding affinity to 5-HT6R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nM ΔG°: -12.3kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Binding affinity to 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 312nMAssay Description:Inhibition of Protein kinase C alpha expressed in Sf-9 cellsMore data for this Ligand-Target Pair