BDBM350257 US10208056, Compound 84

SMILES NC(=O)c1cc2c(-c3ccncc3OC22CCCCC2)n1CCF

InChI Key InChIKey=URTXFNMSFMYZRA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350257   

TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
F.S.P. Cnio

US Patent
LigandPNGBDBM350257(US10208056, Compound 84)
Affinity DataIC50:  1.41nMAssay Description:The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-C/Cyclin-dependent kinase 19(Homo sapiens (Human))
F.S.P. Cnio

US Patent
LigandPNGBDBM350257(US10208056, Compound 84)
Affinity DataIC50:  148nMAssay Description:The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
F.S.P. Cnio

US Patent
LigandPNGBDBM350257(US10208056, Compound 84)
Affinity DataIC50:  42.1nMAssay Description:The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent