BDBM35094 biarylether alcohol quinoline, 5f

SMILES Cc1cnc2c(cccc2c1-c1cccc(Oc2cccc(CO)c2)c1)C(F)(F)F

InChI Key InChIKey=CQEKMSRTDPXHST-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 35094   

TargetOxysterols receptor LXR-alpha [197-447](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM35094(biarylether alcohol quinoline, 5f)
Affinity DataIC50:  10.2nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRalpha coated flash plates. Each concentration of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM35094(biarylether alcohol quinoline, 5f)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRalpha-LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM35094(biarylether alcohol quinoline, 5f)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRbeta-LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta [154-461](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM35094(biarylether alcohol quinoline, 5f)
Affinity DataIC50:  2.10nM EC50:  233nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRbeta coated flash plates. Each concentration of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed