BDBM35226 (S,S)-reboxetine::Reboxetine::Vestra

SMILES CCOc1ccccc1O[C@H]([C@@H]1CNCCO1)c1ccccc1

InChI Key InChIKey=CBQGYUDMJHNJBX-OALUTQOASA-N

Data  26 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 35226   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM35226((S,S)-reboxetine | Reboxetine | Vestra)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of dopamine uptake at cloned DAT in rat brain synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM35226((S,S)-reboxetine | Reboxetine | Vestra)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of serotonin uptake at SERT in rat brain synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM35226((S,S)-reboxetine | Reboxetine | Vestra)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of norepinephrine uptake at NET in rat brain synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed