BDBM35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine

SMILES CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12

InChI Key InChIKey=KVWDHTXUZHCGIO-UHFFFAOYSA-N

Data  180 KI  19 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 35254   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)
Affinity DataKi:  7nMAssay Description:Binding affinity to human dopamine D2L receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)
Affinity DataKi:  185nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)
Affinity DataKi:  3.44E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed