BDBM35641 erk000040::pyrimidylpyrrole, 2

SMILES Cc1cnc(Nc2ccccc2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1

InChI Key InChIKey=PFHKAGAZRDERTK-OAQYLSRUSA-N

Data  6 KI

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 35641   

TargetMitogen-activated protein kinase 1(Human)
Vertex Pharmaceuticals

LigandPNGBDBM35641(erk000040 | pyrimidylpyrrole, 2)
Affinity DataKi: <2nM ΔG°: <-12.1kcal/molepH: 7.5 T: 30°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Human)
Vertex Pharmaceuticals

LigandPNGBDBM35641(erk000040 | pyrimidylpyrrole, 2)
Affinity DataKi:  4nMAssay Description:Photometric_Method2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Human)
Vertex Pharmaceuticals

LigandPNGBDBM35641(erk000040 | pyrimidylpyrrole, 2)
Affinity DataKi:  4nMAssay Description:Assay 1 ...More data for this Ligand-Target Pair