BDBM35714 CHEMBL420762::Mozavaptan::N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]azepine-1-carbonyl)-phenyl]-2-methyl-benzamide::OPC-31260
SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12
InChI Key InChIKey=WRNXUQJJCIZICJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 35714
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of [3H]-AVP from AVP-V1a receptor binding site in rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Second Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Second Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Affinity DataIC50: 1.40E+3nMpH: 7.4 T: 4°CAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMpH: 7.4 T: 4°CAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidneyMore data for this Ligand-Target Pair