BDBM35714 CHEMBL420762::Mozavaptan::N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]azepine-1-carbonyl)-phenyl]-2-methyl-benzamide::OPC-31260

SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12

InChI Key InChIKey=WRNXUQJJCIZICJ-UHFFFAOYSA-N

Data  15 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 35714   

TargetVasopressin V2 receptor(Rat)
Yamanouchi Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  6.10nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V2 receptor(Rat)
Yamanouchi Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  6.36nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  9.42nMAssay Description:Concentration of the compound which inhibit [3H]-AVP binding to human Vasopressin V2 receptor coded HeLa cells by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  9.42nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  9.70nMAssay Description:Binding affinity to vasopressin V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Rat)
Yamanouchi Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  42.3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V1a receptor(Human)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V1a receptor(Rat)
Yamanouchi Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  193nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V1a receptor(Human)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  195nMAssay Description:Binding affinity to vasopressin V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Rat)
Yamanouchi Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  232nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V1a receptor(Rat)
Yamanouchi Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  524nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetOxytocin receptor(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  660nMAssay Description:Binding affinity to oxytocin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Rat)
Yamanouchi Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  1.55E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V1b receptor(Rat)
Yamanouchi Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V1b receptor(Human)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed