BDBM35735 sulfonamide deriv., 7c

SMILES NS(=O)(=O)c1ccc(CCNC(=O)Cc2ccccc2)cc1

InChI Key InChIKey=DIZLDASYQVXHTB-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 35735   

TargetCarbonic anhydrase 5A, mitochondrial(Human)
Istanbul University

LigandPNGBDBM35735(sulfonamide deriv., 7c)
Affinity DataKi:  8.10nM ΔG°:  -11.0kcal/moleT: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Istanbul University

LigandPNGBDBM35735(sulfonamide deriv., 7c)
Affinity DataKi:  8.20nM ΔG°:  -11.0kcal/moleT: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Istanbul University

LigandPNGBDBM35735(sulfonamide deriv., 7c)
Affinity DataKi:  60nM ΔG°:  -9.85kcal/molepH: 7.4 T: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istanbul University

LigandPNGBDBM35735(sulfonamide deriv., 7c)
Affinity DataKi:  67nM ΔG°:  -9.78kcal/molepH: 7.4 T: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2009
Entry Details Article
PubMed