BDBM35740 sulfonamide deriv., 7h

SMILES NS(=O)(=O)c1ccc(NC(=O)Cc2ccncc2)cc1

InChI Key InChIKey=CXBVXOMVANONBT-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35740   

TargetCarbonic anhydrase 2(Human)
Istanbul University

LigandPNGBDBM35740(sulfonamide deriv., 7h)
Affinity DataKi:  74nM ΔG°:  -9.72kcal/moleT: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istanbul University

LigandPNGBDBM35740(sulfonamide deriv., 7h)
Affinity DataKi:  74nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed