BDBM35741 sulfonamide deriv., 7i

SMILES NS(=O)(=O)c1ccc(CCNC(=O)Cc2ccncc2)cc1

InChI Key InChIKey=DWBDLRRSMVHYTQ-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 35741   

TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM35741(sulfonamide deriv., 7i)
Affinity DataKi:  7.60nM ΔG°:  -11.1kcal/moleT: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35741(sulfonamide deriv., 7i)
Affinity DataKi:  8.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM35741(sulfonamide deriv., 7i)
Affinity DataKi:  9.30nM ΔG°:  -10.9kcal/moleT: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35741(sulfonamide deriv., 7i)
Affinity DataKi:  73nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35741(sulfonamide deriv., 7i)
Affinity DataKi:  73nM ΔG°:  -9.73kcal/molepH: 7.4 T: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35741(sulfonamide deriv., 7i)
Affinity DataKi:  97nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35741(sulfonamide deriv., 7i)
Affinity DataKi:  97nM ΔG°:  -9.56kcal/moleT: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed