BDBM35905 Tolfenamic acid::cid_610479::flufenamic acid analogue, 32

SMILES Cc1c(Cl)cccc1Nc1ccccc1C(O)=O

InChI Key InChIKey=YEZNLOUZAIOMLT-UHFFFAOYSA-N

Data  2 KI  8 IC50  1 Kd  1 EC50

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35905   

TargetTransthyretin(Homo sapiens (Human))
Ume£

Curated by ChEMBL
LigandPNGBDBM35905(Tolfenamic acid | cid_610479 | flufenamic acid ana...)
Affinity DataKd:  150nMAssay Description:Binding affinity to TTR (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Ume£

Curated by ChEMBL
LigandPNGBDBM35905(Tolfenamic acid | cid_610479 | flufenamic acid ana...)
Affinity DataIC50:  4.00E+4nMAssay Description:Binding affinity to TTR in human plasma assessed as protein stabilization preincubated for 1 hr followed by urea-mediated denaturation by Western blo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed