BDBM360348 US9828369, Example 5::methyl 3-(8-((1-(4-(trifluoromethyl) phenyl)piperidine-4-carboxamido) methyl)isoquinolin-5-yl)benzoate

SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)C2CCN(CC2)c2ccc(cc2)C(F)(F)F)c2cnccc12

InChI Key InChIKey=AYUAAVPNXFTQNI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360348   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharpe & Dohme

US Patent
LigandPNGBDBM360348(US9828369, Example 5 | methyl 3-(8-((1-(4-(trifluo...)
Affinity DataIC50:  100nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent