BDBM36484 (S)-Benzyl (6-acetamido-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxohexan-2-yl)carbamate, 21::CID10435243

SMILES CC(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccc2c(C)cc(=O)oc2c1

InChI Key InChIKey=QPYCOBUGIVWEDU-QFIPXVFZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 36484   

TargetHistone deacetylase 4(Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM36484((S)-Benzyl (6-acetamido-1-((4-methyl-2-oxo-2H-chro...)
Affinity DataIC50:  643nMpH: 7.4 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM36484((S)-Benzyl (6-acetamido-1-((4-methyl-2-oxo-2H-chro...)
Affinity DataIC50:  1.02E+3nMpH: 7.4 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM36484((S)-Benzyl (6-acetamido-1-((4-methyl-2-oxo-2H-chro...)
Affinity DataIC50:  786nMpH: 7.4 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM36484((S)-Benzyl (6-acetamido-1-((4-methyl-2-oxo-2H-chro...)
Affinity DataIC50:  1.31E+3nMpH: 7.4 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed