BDBM36497 CHEMBL191436::DADMe-ImmA-Bn

SMILES Nc1ncnc2c(CN3CC(O)C(CSCc4ccccc4)C3)c[nH]c12

InChI Key InChIKey=DIGGNILBPCEZIV-UHFFFAOYSA-N

Data  2 KI  7 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 36497   

TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM36497(CHEMBL191436 | DADMe-ImmA-Bn)
Affinity DataKi:  0.700nMAssay Description:Inhibition of human MTAP as equilibrium dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM36497(CHEMBL191436 | DADMe-ImmA-Bn)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human MTAP as initial dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Klebsiella pneumoniae)
Albert Einstein College Of Medicine

LigandPNGBDBM36497(CHEMBL191436 | DADMe-ImmA-Bn)
Affinity DataKd:  1.90nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Staphylococcus aureus)
Albert Einstein College Of Medicine

LigandPNGBDBM36497(CHEMBL191436 | DADMe-ImmA-Bn)
Affinity DataKd:  0.841nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteine nucleosidase(Streptococcus pneumoniae)
Albert Einstein College Of Medicine

LigandPNGBDBM36497(CHEMBL191436 | DADMe-ImmA-Bn)
Affinity DataKd:  2.40nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM36497(CHEMBL191436 | DADMe-ImmA-Bn)
Affinity DataKd:  0.700nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteine nucleosidase(Helicobacter pylori)
Albert Einstein College Of Medicine

LigandPNGBDBM36497(CHEMBL191436 | DADMe-ImmA-Bn)
Affinity DataKd:  200nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Neisseria meningitidis)
Albert Einstein College Of Medicine

LigandPNGBDBM36497(CHEMBL191436 | DADMe-ImmA-Bn)
Affinity DataKd:  0.0240nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Albert Einstein College Of Medicine

LigandPNGBDBM36497(CHEMBL191436 | DADMe-ImmA-Bn)
Affinity DataKd:  0.000460nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair