BDBM36530 D157493

SMILES Nc1nc(N)c2c(OCC3CCN(Cc4cccc(Cl)c4Cl)CC3)cccc2n1

InChI Key InChIKey=XVLUVRFYGVJKGJ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 36530   

Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36530(D157493)
Affinity DataIC50: 43.9nM EC50:  67nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36530(D157493)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)