BDBM394678 4-[({5-[3- (trifluoromethyl) benzoyl]pyrimidin- 2-yl}amino)methyl] benzamide::US10308615, Example 33

SMILES NC(=O)c1ccc(CNc2ncc(cn2)C(=O)c2cccc(c2)C(F)(F)F)cc1

InChI Key InChIKey=DRIOAXWEHSGQOM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 394678   

TargetPantetheinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM394678(4-[({5-[3- (trifluoromethyl) benzoyl]pyrimidin- 2-...)
Affinity DataIC50:  7.30nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPantetheinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM394678(4-[({5-[3- (trifluoromethyl) benzoyl]pyrimidin- 2-...)
Affinity DataIC50:  206nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPantetheinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM394678(4-[({5-[3- (trifluoromethyl) benzoyl]pyrimidin- 2-...)
Affinity DataIC50:  55.9nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent