BDBM395062 (2-{[(6- methylpyridin-3- yl)methyl]amino} pyrimidin-5-yl)[3- (trifluoromethyl) phenyl]methanone::US10308615, Example 73

SMILES Cc1ccc(CNc2ncc(cn2)C(=O)c2cccc(c2)C(F)(F)F)cn1

InChI Key InChIKey=KBMLPTBEXTYAKP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395062   

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM395062(US10308615, Example 73 | (2-{[(6- methylpyridin-3-...)
Affinity DataIC50: 1.70nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM395062(US10308615, Example 73 | (2-{[(6- methylpyridin-3-...)
Affinity DataIC50: 10.6nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM395062(US10308615, Example 73 | (2-{[(6- methylpyridin-3-...)
Affinity DataIC50: 1.20nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In DepthDetails
US Patent