BDBM395801 US10308654, Example 29

SMILES CCN(CC)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n1N1CCCCC1

InChI Key InChIKey=ZPZKPOCQCJOFEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395801   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Changzhou Longthera Pharmaceuticals

US Patent
LigandPNGBDBM395801(US10308654, Example 29)
Affinity DataIC50:  550nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Changzhou Longthera Pharmaceuticals

US Patent
LigandPNGBDBM395801(US10308654, Example 29)
Affinity DataIC50: <10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent