BDBM404346 US10343992, Example 5::US10689345, Example 5::US11053198, Example 5::US11066365, Example 5

SMILES O=C(N[C@@H]1CCN(C1)C#N)N1CC(C1)c1ccccc1

InChI Key InChIKey=GWAKHLLCMROOOR-CQSZACIVSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 404346   

TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Missions Therapeutics

US Patent
LigandPNGBDBM404346(US10343992, Example 5 | US10689345, Example 5 | US...)
Affinity DataIC50:  550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Missions Therapeutics

US Patent
LigandPNGBDBM404346(US10343992, Example 5 | US10689345, Example 5 | US...)
Affinity DataIC50:  550nMAssay Description:USP30 biochemical fluorescence intensity IC50 assay Dilution plates were prepared at 21 times the final concentration (2100 μM for a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Missions Therapeutics

US Patent
LigandPNGBDBM404346(US10343992, Example 5 | US10689345, Example 5 | US...)
Affinity DataIC50:  550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Missions Therapeutics

US Patent
LigandPNGBDBM404346(US10343992, Example 5 | US10689345, Example 5 | US...)
Affinity DataIC50:  550nMAssay Description:USP30 Biochemical Fluorescence Intensity Kinetic Assay.Reactions were performed in duplicate in black 384 well plates (small volume, Greiner 784076) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent