BDBM418821 4-{[4-({3-[(difluoromethyl)(methyl- sulfonyl)amino]benzyl}amino)-5- (trifluoromethyl)pyrimidin-2- yl]amino}benzoate (321)::US10450297, Example 321

SMILES COC(=O)c1ccc(Nc2ncc(c(NCc3cccc(c3)N(C(F)F)S(C)(=O)=O)n2)C(F)(F)F)cc1

InChI Key InChIKey=YLZBGBURGQFQPR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418821   

TargetFocal adhesion kinase 1 [410-689](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM418821(4-{[4-({3-[(difluoromethyl)(methyl- sulfonyl)amino...)
Affinity DataIC50:  449nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent