BDBM419148 N-(4-ethylphenyl)-N- isobutyl-4-(tetrahydropyran- 4- ylmethanesulfinyl)benzene- sulfonamide::US10457637, Compound 13::US10457637, Compound 14

SMILES CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc(cc1)S(=O)CC1CCOCC1

InChI Key InChIKey=HFMXKUVVFZSMNI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 419148   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM419148(N-(4-ethylphenyl)-N- isobutyl-4-(tetrahydropyran- ...)
Affinity DataIC50:  550nMAssay Description:The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM419148(N-(4-ethylphenyl)-N- isobutyl-4-(tetrahydropyran- ...)
Affinity DataIC50:  550nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM419148(N-(4-ethylphenyl)-N- isobutyl-4-(tetrahydropyran- ...)
Affinity DataIC50:  550nMAssay Description:The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM419148(N-(4-ethylphenyl)-N- isobutyl-4-(tetrahydropyran- ...)
Affinity DataIC50:  550nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent