BDBM419162 N-(4-ethylphenyl)-4-((4- fluorotetrahydro-2H-pyran- 4-yl)methoxy)-N-isobutyl-3- (S- methylsulfonimidoyl)benzene- sulfonamide::US10457637, Compound 30

SMILES CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc(OCC2(F)CCOCC2)c(c1)S(C)(=N)=O

InChI Key InChIKey=ZJUUMXKSCMTTAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419162   

TargetInterleukin-17A(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM419162(N-(4-ethylphenyl)-4-((4- fluorotetrahydro-2H-pyran...)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM419162(N-(4-ethylphenyl)-4-((4- fluorotetrahydro-2H-pyran...)
Affinity DataIC50: <100nMAssay Description:The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent