BDBM421052 US10479795, Example 55::tert-Butyl [trans-4-({[3-(8-aminoimidazo[1,2-a]pyrazin-3- yl)-4-methylphenyl]sulfonyl}amino)cyclohexyl]carbamate

SMILES Cc1ccc(cc1-c1cnc2c(N)nccn12)S(=O)(=O)N[C@H]1CC[C@@H](CC1)NC(=O)OC(C)(C)C

InChI Key InChIKey=MVQSIAPYDXLZLE-QAQDUYKDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421052   

LigandPNGBDBM421052(US10479795, Example 55 | tert-Butyl [trans-4-({[3-...)
Affinity DataIC50: >2.00E+3nMAssay Description:PI3Kδ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM421052(US10479795, Example 55 | tert-Butyl [trans-4-({[3-...)
Affinity DataIC50: <100nMAssay Description:PI3K-γ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.)....More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent