BDBM422171 2-butyl-1-(2,6- dimethoxyphenyl)-6- hydroxy-5-(4- methylbenzenesulfonyl)- 1,4-dihydropyrimidin- 4-one::US10508104, Example 62::US10508104, Example 66
SMILES CCCCc1nc(=O)c(c(O)n1-c1c(OC)cccc1OC)S(=O)(=O)c1ccc(C)cc1
InChI Key InChIKey=BLGNPGSXHWXDOA-UHFFFAOYSA-N
Data 5 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 422171
Affinity DataEC50: 5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at mouse APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at rat APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Agonist activity at human APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assayMore data for this Ligand-Target Pair