BDBM427383 (S)-methyl (4-(4-((2-amino-2,4-dimethylpentyl)oxy)phenyl)pyrimidin-2-yl)carbamate::US10544120, Example 505

SMILES CC(C)C[C@@](C)(COc1ccc(cc1)B1OC(C)(C)C(C)(C)O1)NC(=O)OC(C)(C)C

InChI Key InChIKey=SRBGXLVNHFSKKZ-DEOSSOPVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 427383   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM427383((S)-methyl (4-(4-((2-amino-2,4-dimethylpentyl)oxy)...)
Affinity DataIC50:  8.70nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent