BDBM429561 US10550089, Example 35::US10995072, Example 36

SMILES CCc1ccc2c(F)ccc([C@@H](O)c3ncc[nH]3)n12

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 429561   

TargetProteinase-activated receptor 2(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM429561(US10550089, Example 35 | US10995072, Example 36)
Affinity DataIC50:  200nMAssay Description:Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 2(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM429561(US10550089, Example 35 | US10995072, Example 36)
Affinity DataIC50: >4.10E+4nMAssay Description:Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 2(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM429561(US10550089, Example 35 | US10995072, Example 36)
Affinity DataIC50: >1.00E+5nMAssay Description:Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 2(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM429561(US10550089, Example 35 | US10995072, Example 36)
Affinity DataIC50:  1.61E+3nMAssay Description:Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent