BDBM452530 1-((3-((3R,5R)-5-(4- chlorophenyl)tetra- hydrofuran-3-yl)-1,2,4- oxadiazol-5-yl)methyl)- 2,7-dimethyl-1,7- dihydro-6H-purin-6-one::US10710994, Example 110::US10710994, Example 8

SMILES Cc1nc2ncn(C)c2c(=O)n1Cc1nc(no1)[C@@H]1CO[C@H](C1)c1ccc(Cl)cc1

InChI Key InChIKey=FIBJEOLUMVIRIT-DZGCQCFKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 452530   

LigandPNGBDBM452530(1-((3-((3R,5R)-5-(4- chlorophenyl)tetra- hydrofura...)
Affinity DataIC50:  9.38nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM452530(1-((3-((3R,5R)-5-(4- chlorophenyl)tetra- hydrofura...)
Affinity DataIC50:  3.90nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM452530(1-((3-((3R,5R)-5-(4- chlorophenyl)tetra- hydrofura...)
Affinity DataIC50:  9.32nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM452530(1-((3-((3R,5R)-5-(4- chlorophenyl)tetra- hydrofura...)
Affinity DataIC50:  4.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent