BDBM468564 US10806794, Compound mPEG7-O-Darunavir

SMILES COCCOCCOCCOCCOCCOCCOCCOc1ccc(C[C@H](NC(=O)O[C@H]2CO[C@H]3OCC[C@@H]23)C(O)CN(CC(C)C)S(=O)(=O)c2ccc(N)cc2)cc1

InChI Key InChIKey=ABCWSIGLFMCQCE-YRYHPRDQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 468564   

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandPNGBDBM468564(US10806794, Compound mPEG7-O-Darunavir)
Affinity DataIC50:  0.358nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent