BDBM468568 US10806794, Compound mPEG1-OCONH-Tipranavir

SMILES CC[C@@H](C1=C(O)C[C@@](CCCNC(=O)OCCOC)(CCc2ccccc2)OC1=O)c1cccc(NS(=O)(=O)c2ccc(cn2)C(F)(F)F)c1

InChI Key InChIKey=HQBQEKVIFDIRCJ-XQJOSWFISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 468568   

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandPNGBDBM468568(US10806794, Compound mPEG1-OCONH-Tipranavir)
Affinity DataIC50:  0.188nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent