BDBM476299 US10874683, Example 00106::US10874683, Example 56.1::US10874683, Example EIDD-01931-04::US10874683, Example EIDD-02200-01::US10874683, Example EIDD-02261-01::US10874683, Example EIDD-02345-01::US10874683, Example EIDD-02416-01

SMILES OC[C@H]1O[C@H](C(O)[C@H]1O)n1ccc(NO)nc1=O

InChI Key InChIKey=XCUAIINAJCDIPM-JDNPWWSISA-N

Data  10 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 476299   

TargetGenome polyprotein(Hu/NV/NV/1968/US)
Emory University

US Patent
LigandPNGBDBM476299(US10874683, Example 00106 | US10874683, Example 56...)
Affinity DataEC50: >3.86E+6nMAssay Description:Several derivatives of EIDD-01931 have shown antiviral activity in screening against various viruses. Activity data is shown in the tables below. Nor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Emory University

US Patent
LigandPNGBDBM476299(US10874683, Example 00106 | US10874683, Example 56...)
Affinity DataEC50: <380nMAssay Description:Several derivatives of EIDD-01931 have shown antiviral activity in screening against various viruses. Activity data is shown in the tables below. Nor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStructural polyprotein(CHIKV)
Emory University

US Patent
LigandPNGBDBM476299(US10874683, Example 00106 | US10874683, Example 56...)
Affinity DataEC50:  600nMAssay Description:Primary cytopathic effect (CPE) reduction assay. Four-concentration CPE inhibition assays are performed. Confluent or near-confluent cell culture mon...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStructural polyprotein(CHIKV)
Emory University

US Patent
LigandPNGBDBM476299(US10874683, Example 00106 | US10874683, Example 56...)
Affinity DataEC50:  1.80E+3nMAssay Description:Primary cytopathic effect (CPE) reduction assay. Four-concentration CPE inhibition assays are performed. Confluent or near-confluent cell culture mon...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(ZIKV)
Emory University

US Patent
LigandPNGBDBM476299(US10874683, Example 00106 | US10874683, Example 56...)
Affinity DataEC50:  4.02E+3nMAssay Description:Primary cytopathic effect (CPE) reduction assay. Four-concentration CPE inhibition assays are performed. Confluent or near-confluent cell culture mon...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStructural polyprotein(CHIKV)
Emory University

US Patent
LigandPNGBDBM476299(US10874683, Example 00106 | US10874683, Example 56...)
Affinity DataEC50:  2.70E+4nMAssay Description:Primary cytopathic effect (CPE) reduction assay. Four-concentration CPE inhibition assays are performed. Confluent or near-confluent cell culture mon...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStructural polyprotein(CHIKV)
Emory University

US Patent
LigandPNGBDBM476299(US10874683, Example 00106 | US10874683, Example 56...)
Affinity DataEC50:  1.50E+3nMAssay Description:Primary cytopathic effect (CPE) reduction assay. Four-concentration CPE inhibition assays are performed. Confluent or near-confluent cell culture mon...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStructural polyprotein(CHIKV)
Emory University

US Patent
LigandPNGBDBM476299(US10874683, Example 00106 | US10874683, Example 56...)
Affinity DataEC50:  1.50E+3nMAssay Description:Primary cytopathic effect (CPE) reduction assay. Four-concentration CPE inhibition assays are performed. Confluent or near-confluent cell culture mon...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStructural polyprotein(CHIKV)
Emory University

US Patent
LigandPNGBDBM476299(US10874683, Example 00106 | US10874683, Example 56...)
Affinity DataEC50: >7.80E+4nMAssay Description:Primary cytopathic effect (CPE) reduction assay. Four-concentration CPE inhibition assays are performed. Confluent or near-confluent cell culture mon...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStructural polyprotein(CHIKV)
Emory University

US Patent
LigandPNGBDBM476299(US10874683, Example 00106 | US10874683, Example 56...)
Affinity DataEC50:  1.80E+3nMAssay Description:Primary cytopathic effect (CPE) reduction assay. Four-concentration CPE inhibition assays are performed. Confluent or near-confluent cell culture mon...More data for this Ligand-Target Pair
In DepthDetails US Patent