BDBM476922 US10870660, Compound II-078::US11345716, Compound II-078

SMILES Cc1cc(OCC(=O)N[C@H]2CC[C@H](CCN3CCc4ccc(OCC(F)(F)F)nc4CC3)CC2)no1

InChI Key InChIKey=OFNJFDWFNZIXMI-KESTWPANSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 476922   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM476922(US10870660, Compound II-078 | US11345716, Compound...)
Affinity DataKi:  0.0750nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM476922(US10870660, Compound II-078 | US11345716, Compound...)
Affinity DataKi:  0.0750nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM476922(US10870660, Compound II-078 | US11345716, Compound...)
Affinity DataKi: >1.80E+3nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM476922(US10870660, Compound II-078 | US11345716, Compound...)
Affinity DataKi: >1.80E+3nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent