BDBM476924 US10870660, Compound II-084::US11345716, Compound II-084

SMILES CN(CC(F)(F)F)c1nc2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)Cc3cnc(C)s3)CCc2s1

InChI Key InChIKey=OCNSHCHKTREKMB-IYARVYRRSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 476924   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM476924(US10870660, Compound II-084 | US11345716, Compound...)
Affinity DataKi:  0.0520nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM476924(US10870660, Compound II-084 | US11345716, Compound...)
Affinity DataKi:  0.0520nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM476924(US10870660, Compound II-084 | US11345716, Compound...)
Affinity DataKi:  510nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM476924(US10870660, Compound II-084 | US11345716, Compound...)
Affinity DataKi:  510nMAssay Description:225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent