BDBM486274 N-[3-(1-cyclobutyl-5-methyl-6-oxopyridin-3- yl)-4-(2,4-difluorophenoxy)phenyl] methanesulfonamide::US10941160, Example 484

SMILES Cc1cc(cn(C2CCC2)c1=O)-c1cc(NS(C)=O)ccc1Oc1ccc(F)cc1F

InChI Key InChIKey=GFEYCDWOQUMYMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 486274   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM486274(N-[3-(1-cyclobutyl-5-methyl-6-oxopyridin-3- yl)-4-...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent