BDBM486280 N-[2-ethyl-8-(2-methyl-1-oxoisoquinolin-4-yl)- 3,4-difluoro-2H-chromen-6-yl] methanesulfonamide::US10941160, Example 490

SMILES CCC1CCc2cc(NS(C)=O)cc(c2O1)-c1cn(C)c(=O)c2ccccc12

InChI Key InChIKey=MXWBNPDWZMDJMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 486280   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM486280(N-[2-ethyl-8-(2-methyl-1-oxoisoquinolin-4-yl)- 3,4...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent