BDBM486692 US10947252, Example 135::US11427601, Example 135
SMILES CCn1nnc2c(C)c(ccc12)C(CC(O)=O)c1ccc(C)c(CN2C[C@H]3COCCN3c3ncccc3S2(=O)=O)c1
InChI Key InChIKey=MCNYDHMNNGQZKU-LFQPHHBNSA-N
Data 2 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 486692
TargetKelch-like ECH-associated protein 1 [321-624](Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataKd: 1.80nMAssay Description:The details of the KEAP1 KELCH ThermoFluorŪ Assay Construct are as follows: Kelch domain of human KEAP 1 (321-624 aa) was used in the assay. The prot...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataKd: 1.80nMAssay Description:The ThermoFluorŪ is a fluorescence based assay (Tf) that estimates ligand binding affinities by measuring the effect of a ligand on protein thermal s...More data for this Ligand-Target Pair