BDBM494507 (R)-N-(6- (dimethylamino)-2-(2- fluoro-3-hydroxy-3- methylbutyl)-1- oxoisoindolin-5- yl)pyrazolo[1,5-a] pyrimidine-3- carboxamide::US10988478, Example 570

SMILES CN(C)c1cc2C(=O)N(C[C@@H](F)C(C)(C)O)Cc2cc1NC(=O)c1cnn2cccnc12

InChI Key InChIKey=WCFKIXYQEUUKSX-GOSISDBHSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494507   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM494507((R)-N-(6- (dimethylamino)-2-(2- fluoro-3-hydroxy-3...)
Affinity DataKi:  0.630nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent