BDBM498674 (1S,3R)-3-(3-{[(3,5- difluorophenyl)acetyl]amino}- 1H-pyrazol-5-yl)cyclopentyl [(2S)-tetrahydrofuran-2- ylmethyl]carbamate::US11014911, Example 499::US11718603, Example 499

SMILES Fc1cc(F)cc(CC(=O)Nc2cc([nH]n2)[C@@H]2CC[C@@H](C2)OC(=O)NC[C@@H]2CCCO2)c1

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 498674   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM498674((1S,3R)-3-(3-{[(3,5- difluorophenyl)acetyl]amino}...)
Affinity DataKi:  2.55nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM498674((1S,3R)-3-(3-{[(3,5- difluorophenyl)acetyl]amino}...)
Affinity DataKi:  2.55nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent