BDBM50001839 CHEMBL428647::PACLITAXEL::taxol
SMILES CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c3ccccc3)[C@@H]3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c1ccccc1)c1ccccc1
InChI Key InChIKey=RCINICONZNJXQF-MZXODVADSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50001839
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of MDR1 (unknown origin) transfected in human SKOV3 cells assessed as growth inhibition after 48 hrs by SRB assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of p-gp overexpressed in human SKOV3/M6-6 isogenic cells after 48 hrs by sulforhodamine B assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Inhibition of beta3 tubulin overexpressed in human HeLa cells after 48 hrs by SRB assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Inhibition of beta3 Tubulin (unknown origin) expressed in human HeLa cell line assessed as inhibition of cell proliferation measured after 48 hrs by ...More data for this Ligand-Target Pair