BDBM50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15

SMILES CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12

InChI Key InChIKey=ZPEIMTDSQAKGNT-UHFFFAOYSA-N

Data  238 KI  77 IC50  4 Kd  9 EC50

PDB links: 10 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50001888   

TargetMajor prion protein(Mus musculus)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataEC50:  2.00E+3nMAssay Description:Activity at mouse prion protein expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetOrf1a protein(MERS-CoV)
University Of Bonn

LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataEC50:  4.90E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataEC50:  8.80E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
University Of Bonn

LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataEC50:  2.50E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrf1a protein(MERS-CoV)
University Of Bonn

LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataEC50:  9.51E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataEC50:  1.30E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit alpha type-6(Homo sapiens (Human))
Michigan State University

LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataEC50:  1.48E+4nMpH: 7.5 T: 2°CAssay Description:Activity assays were carried out in a 200 uL reaction volume. Different concentrations of test compounds were added to a black flat/clear bottom 96-w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit alpha type-6(Homo sapiens (Human))
Michigan State University

LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataEC50:  9.90E+3nMpH: 7.5 T: 2°CAssay Description:Activity assays were carried out in a 200 uL reaction volume. Different concentrations of test compounds were added to a black flat/clear bottom 96-w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMajor prion protein(Homo sapiens (Human))
Institut F£R Molekularbiologie Und Biophysik

Curated by ChEMBL
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataEC50:  2.00E+3nMAssay Description:Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cellsMore data for this Ligand-Target Pair