BDBM50004823 (6aS,13bR)-11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::(6aS,13bR)-11-chloro-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepin-12-ol::11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::CHEMBL298406::Ecopipam::SCH 39166::trans-(-) 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol

SMILES CN1CCc2cc(Cl)c(O)cc2[C@@H]2[C@@H]1CCc1ccccc21

InChI Key InChIKey=DMJWENQHWZZWDF-UHFFFAOYSA-N

Data  17 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50004823   

TargetD(1A) dopamine receptor(Rat)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004823BDBM50004823(CHEMBL298406 | Ecopipam | SCH 39166 | (6aS,13bR)-1...)
Affinity DataKi:  1.90nMAssay Description:In vitro affinity of compound towards dopamine (D1) receptor was determined by measuring their ability to displace [3H]SCH-23,390 from rat striatal h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004823BDBM50004823(CHEMBL298406 | Ecopipam | SCH 39166 | (6aS,13bR)-1...)
Affinity DataKi:  3.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Schering-Plough

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50004823BDBM50004823(CHEMBL298406 | Ecopipam | SCH 39166 | (6aS,13bR)-1...)
Affinity DataKi:  321nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004823BDBM50004823(CHEMBL298406 | Ecopipam | SCH 39166 | (6aS,13bR)-1...)
Affinity DataKi:  514nMAssay Description:Displacement of [3H]spiperone from rat striatal homogenate dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004823BDBM50004823(CHEMBL298406 | Ecopipam | SCH 39166 | (6aS,13bR)-1...)
Affinity DataKi:  4.27E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed