BDBM50005482 CHEMBL140772::CHEMBL3234252
SMILES CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)NC1CCN(CC1)C(C)=O
InChI Key InChIKey=OCAANUCNWHJWBD-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50005482
Affinity DataIC50: 270nMAssay Description:Antagonist activity at Gal4-fused RORgamma (unknown origin) expressed in 293T cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institutes Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: 7.55E+3nMAssay Description:Inhibition of human His6-tagged BRD4 bromodomain 1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) cells using biotin-H4KAc4 as substr...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Antagonist activity at full-length RORgamma (unknown origin) expressed in 293T cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair