BDBM50006784 3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid isopropyl ester::CHEMBL82946::RTI-121

SMILES CC(C)OC(=O)[C@@H]1C2CC[C@H](C[C@@H]1c1ccc(I)cc1)N2C

InChI Key InChIKey=ZAQLTGAFVMGUMB-UHFFFAOYSA-N

Data  4 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50006784   

TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006784(CHEMBL82946 | RTI-121 | 3-(4-Iodo-phenyl)-8-methyl...)
Affinity DataIC50: 864nMAssay Description:Inhibition of [3H]mazindol binding to Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006784(CHEMBL82946 | RTI-121 | 3-(4-Iodo-phenyl)-8-methyl...)
Affinity DataIC50: 310nMAssay Description:Inhibition of [3H]paroxetine binding to Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006784(CHEMBL82946 | RTI-121 | 3-(4-Iodo-phenyl)-8-methyl...)
Affinity DataIC50: 0.430nMAssay Description:Compound was evaluated for the inhibition of [3H]WIN-35428l binding to dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006784(CHEMBL82946 | RTI-121 | 3-(4-Iodo-phenyl)-8-methyl...)
Affinity DataIC50: 285nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006784(CHEMBL82946 | RTI-121 | 3-(4-Iodo-phenyl)-8-methyl...)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006784(CHEMBL82946 | RTI-121 | 3-(4-Iodo-phenyl)-8-methyl...)
Affinity DataIC50: 67nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006784(CHEMBL82946 | RTI-121 | 3-(4-Iodo-phenyl)-8-methyl...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006784(CHEMBL82946 | RTI-121 | 3-(4-Iodo-phenyl)-8-methyl...)
Affinity DataKi:  4nMAssay Description:Binding affinity to dopamine transporter (DAT) using [3H]WIN-35428 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006784(CHEMBL82946 | RTI-121 | 3-(4-Iodo-phenyl)-8-methyl...)
Affinity DataKi:  66.8nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNorepinephrine transporter(Rat)
Virginia Commonwealth University

Curated by PDSP Ki Database
LigandPNGBDBM50006784(CHEMBL82946 | RTI-121 | 3-(4-Iodo-phenyl)-8-methyl...)
Affinity DataKi:  285nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed