BDBM50007548 (S)-2-Amino-4-phosphono-butyric acid::(S)-2-amino-4-phosphonobutanoic acid::2-Amino-3-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl)-propionic acid::2-Amino-4-phosphono-butyric acid::2-Amino-4-phosphono-butyric acid(S-AP4)::2-amino-4-phosphonobutanoic acid::2-amino-4-phosphonobutyric acid::CHEMBL33567::L-(+)-2-amino-4-phosphonobutyric acid::L-1-amino-4-phosphonobutanoic acid::L-AP4::L-APB
SMILES N[C@@H](CCP(O)(O)=O)C(O)=O
InChI Key InChIKey=DDOQBQRIEWHWBT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 97 hits for monomerid = 50007548
Affinity DataEC50: 2.49E+5nMAssay Description:Agonist activity at rat mGlu7 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+6nMAssay Description:Activity at rat mGluR1 by measuring intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 340nMAssay Description:Activity at rat mGluR6 by measuring cAMP formation in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 510nMAssay Description:Functional activity at rat mGluR4More data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Effective concentration against Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
Affinity DataEC50: 1.29E+5nMAssay Description:Effective concentration against D309A mutant Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
Affinity DataEC50: 320nMAssay Description:Stimulation od [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.37E+5nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 290nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: >1.00E+6nMAssay Description:Activity at human mGluR2 from BHK cells in [35S]GTP-gamma-S stimulation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 310nMAssay Description:Activation of human metabotropic glutamate 4 receptor expressed in golden hamster AV12-664 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Activation of human metabotropic glutamate 8 receptor expressed in golden hamster AV12-664 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Activation of human metabotropic glutamate 6 receptor expressed in golden hamster AV12-664 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells coexpressing Gq/Gi and EAAC1 assessed as intracellular calcium production measured e...More data for this Ligand-Target Pair
Affinity DataEC50: 570nMAssay Description:Effect on Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+6nMAssay Description:Effect on Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+6nMAssay Description:Effect on Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
Affinity DataEC50: 340nMAssay Description:Activity at rat recombinant mGluR6 expressed in CHO cells assessed as cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 96nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Agonist activity at rat mGlu8 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Agonist activity at rat mGlu8 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.06E+5nMAssay Description:Agonist activity at rat mGlu7 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
Affinity DataEC50: 2.49E+5nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at rat mGlu6 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+6nMAssay Description:Effect on Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+6nMAssay Description:Activity at human recombinant mGluR2 expressed in BHK cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 1.88E+5nMAssay Description:Activity at human recombinant mGluR7 expressed in BHK cells assessed as cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 510nMAssay Description:Agonist activity at rat recombinant mGluR4 expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+6nMAssay Description:Activity at rat recombinant mGluR5 expressed in CHO cells assessed as intracellular calcium concentrationMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+6nMAssay Description:Activity at rat recombinant mGluR1 expressed in CHO cells assessed as intracellular calcium concentrationMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+6nMAssay Description:Activity at rat mGluR5 by measuring intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.30E+3nMAssay Description:Agonist activity at rat mGlu6 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.88E+5nMAssay Description:Activity at human mGluR7 by measuring cAMP formation in BHK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Metabotropic glutamate receptor 8 agonist activity against forskolin stimulated c-AMP formation in rat non neuronal cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.52E+5nMAssay Description:Effect on Metabotropic glutamate receptor 7More data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
Affinity DataEC50: 2.08E+3nMAssay Description:Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Agonist activity at rat mGluR8 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.26E+5nMAssay Description:Agonist activity at rat mGluR7 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.45E+3nMAssay Description:Agonist activity at rat mGluR6 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Agonist activity at rat mGluR4 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.75E+5nMAssay Description:Metabotropic glutamate receptor 7 agonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Metabotropic glutamate receptor 3 agonist activity against forskolin stimulated c-AMP formation in rat non neuronal cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Metabotropic glutamate receptor 5 agonist activity as basal [3H]- IP formation in ratMore data for this Ligand-Target Pair
Affinity DataEC50: 4.40E+5nMAssay Description:Agonist activity at rat mGluR7 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair