BDBM50015316 CHEMBL3263873

SMILES [H][C@@]1([#6]-[#6][C@@]2([H])\[#6](-[#6]-[#6]-[#6][C@]12[#6])=[#6]\[#6]=[#6]-1\[#6]-[#6@@H](-[#8])-[#6](=[#6])-[#6@H](-[#8])-[#6]-1)[#6@H](-[#6])-[#6]C#C[#6@@H](-[#8])-[#6]C12[#6]-[#6]-3-[#6]-[#6](-[#6]-[#6](-[#6]-3)-[#6]1)-[#6]2

InChI Key InChIKey=UFJLHOSCLNTAFF-NWNPMFOZSA-N

Data  1 IC50  5 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50015316   

TargetVitamin D3 receptor(Homo sapiens (Human))
Rikkyo University

Curated by ChEMBL
LigandPNGBDBM50015316(CHEMBL3263873)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Rikkyo University

Curated by ChEMBL
LigandPNGBDBM50015316(CHEMBL3263873)
Affinity DataEC50:  1.10nMAssay Description:Transactivation of human VDR expressed in HEK293 cells cotransfected with mouse VDRE, Tk-Sppx3-LUC reporter plasmid measured after 24 hrs by lucifera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Rikkyo University

Curated by ChEMBL
LigandPNGBDBM50015316(CHEMBL3263873)
Affinity DataEC50:  2.80nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-NCoR2 and 4-tk-LUC assessed as inhibition of NCoR2 binding to VDR by mammali...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Rikkyo University

Curated by ChEMBL
LigandPNGBDBM50015316(CHEMBL3263873)
Affinity DataEC50:  14nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-SRC1 and 4-tk-LUC assessed as SRC1 interaction with AF2 surface of VDR by ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Rikkyo University

Curated by ChEMBL
LigandPNGBDBM50015316(CHEMBL3263873)
Affinity DataEC50:  1.80nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-N-CoR and 4-tk-LUC assessed as inhibition of N-CoR binding to VDR by mammali...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Rikkyo University

Curated by ChEMBL
LigandPNGBDBM50015316(CHEMBL3263873)
Affinity DataEC50:  0.800nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-RXRalpha and 4-tk-LUC assessed as heterodimerization with RXRalpha by mammal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed